{"product_id":"biolegend-334105","title":"Biolegend, 334105, PE anti-human CD71 Antibody, 25tests","description":"\u003cp\u003eCD71 is a 95 kD type II homodimeric transmembrane glycoprotein also known as T9 and transferrin receptor. It is expressed on proliferating cells, reticulocytes, and erythroid precursors. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: NALM-6 pre-B cell line\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.\u003cbr\u003e\nProduct Citations: Perik-Zavodskii R, et al. 2022. Genes (Basel). 13: . PubMed Segal JM, et al. 2019. Nat Commun. 10:3350. PubMed Angiari S, et al. 2020. Cell Metab. 31:391. PubMed Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed Pérez-Quintero L, et al. 2014. J Exp Med. 211:727. PubMed Turner JS, et al. 2021. Nature. 596:109. PubMed Himadewi P, et al. 2021. Elife. 10:. PubMed Liu S, et al. 2021. Mol Ther. 29:1918. PubMed Morrison TA, et al. 2018. Blood Cells Mol Dis. 69:1. PubMed Davis CW et al. 2019. Cell. 177(6):1566-1582 . PubMed Kanemasa H, et al. 2021. Sci Rep. 11:14396. PubMed Ochi K, et al. 2014. Stem Cells Trans Med. 3:792. PubMed Turner JS, et al. 2020. Nature. 586:127. PubMed Yang W, et al. 2015. PLoS One. 10: 0134995. PubMed Lai Y, et al. 2022. Clin Transl Med. 12:e999. PubMed Mndez-Mancilla A, et al. 2021. Cell Chemical Biology. 29:321. PubMed Hollevoet K, et al. 2014. Mol Cancer Ther. 13:2040. PubMed Hollevoet K, et al. 2015. PLoS One. 10:122462. PubMed Asada S, et al. 2018. Nat Commun. 9:2733. PubMed Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed Dyson MR, et al. 2020. MAbs. 12:1829335. PubMed Turner JS, et al. 2021. Nature. 595:421. PubMed Hill DL, et al. 2019. J Exp Med. 216:1857. PubMed Perik-Zavodskii R, et al. 2022. Genes (Basel). 13:. PubMed\u003cbr\u003e\nRRID: AB_2271603 (BioLegend Cat. No. 334105) AB_2201481 (BioLegend Cat. No. 334106)\u003cbr\u003e\nStructure: Transferrin receptor family, type II glycoprotein, 95 kD\u003cbr\u003e\nDistribution: Proliferating cells, reticulocytes, erythroid precursors\u003cbr\u003e\nFunction: Mediates uptake of iron\u003cbr\u003e\nLigand\/Receptor: Transferrin\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Hentze M, et al. 1996. P. Natl. Acad. Sci. USA 93:8175. 2. Trowbridge I, et al. 1993. Annu. Rev. Cell Biol. 9:129.\u003cbr\u003e\nGene ID: 7037\u003cbr\u003e\nUniProt: View information about CD71 on UniProt.org\u003cbr\u003e\nClone: CY1G4\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: A015\u003cbr\u003e\nOther Names: T9, Transferrin receptor\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862999814313,"sku":"334105","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-334105","provider":"Iright","version":"1.0","type":"link"}