{"product_id":"biolegend-334110","title":"Biolegend, 334110, APC\/Cyanine7 anti-human CD71 Antibody, 100tests","description":"\u003cp\u003eCD71 is a 95 kD type II homodimeric transmembrane glycoprotein also known as T9 and transferrin receptor. It is expressed on proliferating cells, reticulocytes, and erythroid precursors. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: NALM-6 pre-B cell line\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.\u003cbr\u003e\nProduct Citations: Shi H, et al. 2016. Sci Rep. 6:28789. PubMed Chernyshev M, et al. 2023. Nat Commun. 14:2249. PubMed Kaku CI, et al. 2023. Nat Commun. 14:2751. PubMed Andrews SF et al. 2019. Immunity. 51(2):398-410 . PubMed Figueroa-Romero C, et al. 2022. Front Immunol. 13:773288. PubMed Celik H, et al. 2021. Cancer Discov. 11:3126. PubMed Sun J et al. 2018. Cell stem cell. 23(3):355-369 . PubMed Sakharkar M, et al. 2021. Sci Immunol. :6. PubMed\u003cbr\u003e\nRRID: AB_2563116 (BioLegend Cat. No. 334109) AB_2563117 (BioLegend Cat. No. 334110)\u003cbr\u003e\nStructure: Transferrin receptor family, type II glycoprotein, 95 kD\u003cbr\u003e\nDistribution: Proliferating cells, reticulocytes, erythroid precursors\u003cbr\u003e\nFunction: Mediates uptake of iron\u003cbr\u003e\nLigand\/Receptor: Transferrin\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Hentze M, et al. 1996. P. Natl. Acad. Sci. USA 93:8175. 2. Trowbridge I, et al. 1993. Annu. Rev. Cell Biol. 9:129.\u003cbr\u003e\nGene ID: 7037\u003cbr\u003e\nUniProt: View information about CD71 on UniProt.org\u003cbr\u003e\nClone: CY1G4\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: A015\u003cbr\u003e\nOther Names: T9, Transferrin receptor\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862999617705,"sku":"334110","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-334110","provider":"Iright","version":"1.0","type":"link"}