{"product_id":"biolegend-337507","title":"Biolegend, 337507, PE anti-human CD155 (PVR) Antibody, 25tests","description":"\u003cp\u003eCD155, known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. It is a nectin-like molecule belonging to Ig superfamily. CD155 is primarily found on endothelial cells, monocytes, epithelia and central nervous system. CD155 is an adhesion molecule involved in cell-cell and cell-matrix adhesion through interaction with CD226, CD96 (Tactile), nectin-1, -2, and -3 (CD111, CD112, CD113), and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications include: partially inhibits NK- and T-cell mediated cytotoxicity\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Tahara-Hanaoka S, et al. 2004. Intl. Immunol. 16:533\u003cbr\u003e\nProduct Citations: Ohtsuki S, et al. 2023. Cell Rep Med. 101012:4. PubMed Yao C, et al. 2018. Autophagy. 1.854861111. PubMed Kaito Y, et al. 2022. Oncol Lett. 23:51. PubMed Siew Y, et al. 2015. Int Immunol. 27: 621 - 632. PubMed\u003cbr\u003e\nRRID: AB_1279094 (BioLegend Cat. No. 337507) AB_1279092 (BioLegend Cat. No. 337508)\u003cbr\u003e\nStructure: Type I glycoprotein, Ig superfamily\u003cbr\u003e\nDistribution: Monocytes, endothelial cells, epithelia, central nervous system\u003cbr\u003e\nLigand\/Receptor: CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus\u003cbr\u003e\nCell Type: Monocytes, Endothelial cells, Epithelial cells, Tregs\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors\u003cbr\u003e\nAntigen References: 1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley \u0026amp; Sons Inc, Publication 2. Fuchs A, et al. 2004. J. Immunol. 172:3994 3. Bottino PD, et al. 2005. Mol. Immunol. 42:463\u003cbr\u003e\nGene ID: 5817\u003cbr\u003e\nUniProt: View information about CD155 on UniProt.org\u003cbr\u003e\nClone: TX24\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Poliovirus receptor (PVR), nectin-like 5\u003cbr\u003e\nIsotype: Mouse IgG2a, λ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864057860265,"sku":"337507","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-337507","provider":"Iright","version":"1.0","type":"link"}