{"product_id":"biolegend-341203","title":"Biolegend, 341203, Alexa Fluor® 647 anti-human CD160 Antibody, 25tests","description":"\u003cp\u003eCD160 is a 27 kD GPI-anchored glycoprotein also known as BY55, NK1, and NK28. A member the Ig superfamily, CD160 exists as a disulfide-bond multimer, expressed on the surface of a subpopulation of NK cells, γ\/δ T cells, subset of CD8+ T cells, and intestinal intraepithelial lymphocytes (IEL). CD160 plays costimulatory roles through binding to classical and nonclassical MHC-I molecules.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm \/ 635nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Anumanthan A, et al. 1998. J. Immunol. 161:2780. Maiza H, et al. 1993. J. Exp. Med. 178:1121.\u003cbr\u003e\nProduct Citations: Gaballa MR, et al. 2022. Blood. 139:1908. PubMed Cosgrove C, et al. 2014. PLoS One. 9:105950. PubMed Bouma G, et al. 2013. Mol Immunol. 54:472. PubMed Barman S, et al. 2016. Int Immunol. 28: 533 - 545. PubMed Perreau M, et al. 2014. J Exp Med. 211:2033. PubMed\u003cbr\u003e\nRRID: AB_2260001 (BioLegend Cat. No. 341203) AB_2074410 (BioLegend Cat. No. 341204)\u003cbr\u003e\nStructure: 27 kD GPI-anchored glycoprotein, Ig superfamily\u003cbr\u003e\nDistribution: Subpopulation of NK cells, γ\/δ T cells, subset of CD8+ T cells, and intestinal intraepithelial lymphocytes (IEL)\u003cbr\u003e\nFunction: Costimulation\u003cbr\u003e\nLigand\/Receptor: Classical and nonclassical MHC-I molecules\u003cbr\u003e\nCell Type: NK cells, T cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley \u0026amp; Sons Inc, Publication. 2. Merino J, et al. 2007. Clin. Exp. Immunol. 149:87. 3. Barakonyi A, et al. 2004. J. Immunol. 173:5349.\u003cbr\u003e\nGene ID: 11126\u003cbr\u003e\nUniProt: View information about CD160 on UniProt.org\u003cbr\u003e\nClone: BY55\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: BY55, NK1, NK28\u003cbr\u003e\nIsotype: Mouse IgM, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862931525801,"sku":"341203","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-341203","provider":"Iright","version":"1.0","type":"link"}