{"product_id":"biolegend-355504","title":"Biolegend, 355504, PE anti-human CD56 (Subset MSC Marker) Antibody, 100tests","description":"\u003cp\u003eCD56 is a single transmemberane glycoprotein also known as NCAM (neural cell adhesion molecule). It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: KG1a cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Clone 39D5 recognizes the epitope of CD56 that is selectively expressed on a subset of mesenchymal stem cells (MSC) population which are CD271bright cells. It does not efficiently recognize natural killer cells.\u003cbr\u003e\nProduct Citations: Toriyama M, et al. 2023. Front Mol Biosci. 10:1149828. PubMed Peck BD, et al. 2022. FASEB J. 36:e22155. PubMed de Andrade LF, et al. 2019. JCI Insight. 4:e133103. PubMed Guo M, et al. 2021. Front Oncol. 11:632540. PubMed Motedayyen H, et al. 2017. BMC Res Notes. . 10.1186\/s13104-017-2880-6. PubMed\u003cbr\u003e\nRRID: AB_2561552 (BioLegend Cat. No. 355503) AB_2561553 (BioLegend Cat. No. 355504)\u003cbr\u003e\nDistribution: Mesenchymal stem cells\u003cbr\u003e\nCell Type: Mesenchymal Stem Cells\u003cbr\u003e\nBiology Area: Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Stem Cells, Synaptic Biology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Battula VL, et al. 2009. Haematologica 94:173.\u003cbr\u003e\nGene ID: 4684\u003cbr\u003e\nUniProt: View information about CD56 on UniProt.org\u003cbr\u003e\nClone: 39D5\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: V NK57\u003cbr\u003e\nOther Names: NCAM-1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862384562345,"sku":"355504","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-355504","provider":"Iright","version":"1.0","type":"link"}