{"product_id":"biolegend-366005","title":"Biolegend, 366005, Brilliant Violet 605™ anti-human CD105 (Endoglin) Recombinant Antibody, 25tests","description":"\u003cp\u003eEndoglin (CD105) is a type I membrane glycoprotein that is part of the TGF beta receptor complex. It is expressed in vascular endothelial tissue as well as a variety of other tissues. Endoglin may also be involved in the cytoskeletal organization affecting cell morphology and migration.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: EDG (CD105) isolated from acute lymphoblastic leukemia cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610\/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd. Learn more about Brilliant Violet™. This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nRRID: AB_3083356 (BioLegend Cat. No. 366005) AB_3083356 (BioLegend Cat. No. 366006)\u003cbr\u003e\nCell Type: Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Mesenchymal Stem Cells, Monocytes\u003cbr\u003e\nBiology Area: Angiogenesis, Cell Biology, Immunology, Stem Cells\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Li C, et al. 2003. Br J Cancer. 88:1424. Sanz-Rodriguez F, et al. 2004. J Biol Chem. 279(31):32858-68. Takahashi N, et al. 2001. Clin Cancer Res. 7(3):524-32. Seon BK, et al. 1997. Clin Cancer Res. 3(7):1031-44. Haruta Y \u0026amp; Seon BK. 1986. Proc Natl Acad Sci U S A. 83: 7898-902.\u003cbr\u003e\nGene ID: 2022\u003cbr\u003e\nUniProt: View information about CD105 on UniProt.org\u003cbr\u003e\nClone: QA19A14\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Endoglin, Cell surface MJ7\/18 antigen, END, Edg, ENG, HHT1, ORW1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866186633385,"sku":"366005","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-366005","provider":"Iright","version":"1.0","type":"link"}