{"product_id":"biolegend-366918","title":"Biolegend, 366918, Biotin anti-human IgG Fc Recombinant Antibody, 100μg","description":"\u003cp\u003eIgG Fc is a homodimer composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Anti-human IgG Fc antibody (clone QA19A42) may cross-react with bovine IgG. Anti-human IgG Fc antibody (clone M1310G05) does not exhibit this cross-reactivity.\u003cbr\u003e\nProduct Citations: Jaycox JR, et al. 2023. Nat Commun. 14:1299. PubMed\u003cbr\u003e\nRRID: AB_2890797 (BioLegend Cat. No. 366918)\u003cbr\u003e\nStructure: Homodimer formed by the constant region of the IgG heavy chain\u003cbr\u003e\nLigand\/Receptor: CD16, CD32, CD64\u003cbr\u003e\nCell Type: B cells, Basophils, Dendritic cells, Macrophages, Mast cells, Neutrophils, NK cells, Platelets\u003cbr\u003e\nBiology Area: Adaptive Immunity, Cell Biology, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Fc Receptors\u003cbr\u003e\nAntigen References: Paul WE. 2003. Fundamental Immunology. Lippincott Williams \u0026amp; Wilkins. Philadelphia PA.\u003cbr\u003e\nGene ID: 3500\u003cbr\u003e\nUniProt: View information about IgG Fc on UniProt.org\u003cbr\u003e\nClone: QA19A42\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Immunoglobulin G\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: How many biotin molecules are per antibody structure?\u003cbr\u003e\nA: We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866189123753,"sku":"366918","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-366918","provider":"Iright","version":"1.0","type":"link"}