{"product_id":"biolegend-368921","title":"Biolegend, 368921, PerCP\/Fire™ 806 anti-human GPR183 (EBI2) Antibody, 25tests","description":"\u003cp\u003eGPR183, also known as EBI2, is a member of the rhodopsin-like subfamily of 7TM receptors, which forms homodimers and heterodimers when it associates with CXCR5. GPR183 is expressed by Naive B cells, subset of T cells, monocytes and macrophages, and is highly upregulated by Epstein–Barr virus infection. GPR183 regulates the B cell trafficking within lymphoid follicles in response to 7α, 25-dihydroxycholesterol.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human GPR183-transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PerCP\/Fire™ 806 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * PerCP\/Fire™ 806 has a maximum excitation of 478 nm and a maximum emission of 806 nm.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nRRID: AB_3683396 (BioLegend Cat. No. 368921) AB_3683396 (BioLegend Cat. No. 368922)\u003cbr\u003e\nStructure: Member of the rhodopsin-like subfamily of 7TM receptors and forms homo- and heterodimers.\u003cbr\u003e\nDistribution: Naive B cells, subset of T cells, monocytes and macrophages\u003cbr\u003e\nFunction: Chemotactic receptor that regulates B cell trafficking within lymphoid follicles.\u003cbr\u003e\nLigand\/Receptor: 7α, 25-dihydroxycholesterol\u003cbr\u003e\nCell Type: B cells, Macrophages, Monocytes, T cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Cytokine\/Chemokine Receptors, Steroid Receptors\/Nuclear Receptors\u003cbr\u003e\nAntigen References: 1. Preuss I, et al. 2014. Biochem. Biophys. Res. Commun. 446:663. 2. Barroso R, et al. 2012. FASEB J. 26:4841. 3. Hannedouche S, et al. 2011. Nature. 475:524. 4. Benned-Jensen T, et al. 2011. J. Biol. Chem. 286:29292.\u003cbr\u003e\nGene ID: 1880\u003cbr\u003e\nUniProt: View information about GPR183 on UniProt.org\u003cbr\u003e\nClone: SA313E4\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: EBI2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866291982505,"sku":"368921","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-368921","provider":"Iright","version":"1.0","type":"link"}