{"product_id":"biolegend-381607","title":"Biolegend, 381607, PE anti-human CD33 Antibody, 25tests","description":"\u003cp\u003eCD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells, and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes, and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate\/lectin binding activity.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Clone S21002A can completely block the binding of clone P67.6 and WM53 to target cells.\u003cbr\u003e\nRRID: AB_3717003 (BioLegend Cat. No. 381607) AB_3717003 (BioLegend Cat. No. 381608)\u003cbr\u003e\nStructure: Ig superfamily, sialoadhesins, type I glycoprotein, 67 kD\u003cbr\u003e\nDistribution: Myeloid progenitor, monocytes, granulocytes, dendritic cells, mast cells\u003cbr\u003e\nFunction: Adhesion and lectin activity\u003cbr\u003e\nInteraction: Dendritic cells, granulocytes, hematopoietic stem and progenitors, mast cells, monocytes, neutrophils\u003cbr\u003e\nLigand\/Receptor: Sugar chains containing sialic acid\u003cbr\u003e\nCell Type: Dendritic cells, Granulocytes, Hematopoietic stem and progenitors, Mast cells, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules, Siglec Molecules\u003cbr\u003e\nAntigen References: Favaloro E, et al. 1988. Br J Haematol. 69:163-71. Freeman S, et al. 1995. Blood 85:2005-12.\u003cbr\u003e\nGene ID: 945\u003cbr\u003e\nUniProt: View information about CD33 on UniProt.org\u003cbr\u003e\nClone: S21002A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Siglec-3, gp67, p67\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866270519465,"sku":"381607","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-381607","provider":"Iright","version":"1.0","type":"link"}