{"product_id":"biolegend-385704","title":"Biolegend, 385704, Cell-Vive™ GMP Ultra-LEAF™ Purified anti-HU CD69 RecAb SF, 1mg","description":"\u003cp\u003eCD69, also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3, is a 27-33 kD type II transmembrane protein. It is a member of the C-type lectin family and expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells. BioLegend Cell-Vive™ GMP Ultra-LEAF™ antibodies are manufactured and tested in accordance with USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and Ph. Eur. Chapter 5.2.12 in a dedicated GMP facility compliant with ISO 13485:2016. Specifications and processes include\u003cbr\u003e\n1mg\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: 0.1 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is \u0026lt; 0.01 EU\/µg of the protein (\u0026lt; 0.001 ng\/µg of the protein) as determined by the LAL test.\u003cbr\u003e\nEndotoxin Level: Less than 0.01 EU\/μg of the protein (\u0026lt; 0.001 ng\/μg of the protein) as determined by the LAL test\u003cbr\u003e\nConcentration: 1.0 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone QA18A26 can completely block the binding of clone FN50 on target cells. This GMP Ultra-LEAF™ Purified antibody (Endotoxin \u0026lt; 0.01 EU\/µg, Azide-Free, 0.1 µm filtered) is recommended for highly sensitive assays.\u003cbr\u003e\nDisclaimer: BioLegend Cell-Vive™ GMP Ultra-LEAF™ antibodies are for research use only. Suitable for ex vivo cell processing. Not for injection or diagnostic or therapeutic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.\u003cbr\u003e\nStructure: C-type lectin, type II glycoprotein, 28\/32 kD\u003cbr\u003e\nDistribution: Activated T cells, B cells, NK cels, Granulocytes, thymocytes, platelets, Langerhans cells\u003cbr\u003e\nFunction: Lymphocyte, monocyte, and platelet activation, NK cell killing\u003cbr\u003e\nLigand\/Receptor: Galectin-1, S100A8\/S100A9 complex, myosin light chains 9 and 12, and oxidized low-density lipoprotein\u003cbr\u003e\nAntigen References: Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. Marzio R, et al. 1999. Immunopharmacol Immunotoxicol. 21:565-82.\u003cbr\u003e\nGene ID: 969\u003cbr\u003e\nUniProt: View information about CD69 on UniProt.org\u003cbr\u003e\nClone: QA18A26\u003cbr\u003e\nOther Names: Very Early Activation Antigen (VEA), Activation inducer molecule (AIM)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866526601385,"sku":"385704","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-385704","provider":"Iright","version":"1.0","type":"link"}