{"product_id":"biolegend-388204","title":"Biolegend, 388204, PE anti-human CD154 (CD40L) Antibody, 100tests","description":"\u003cp\u003eCD154, also known as CD40L, TNFSF5, T-BAM, and gp39, is a 32-39 kD type II transmembrane glycoprotein member of the TNF superfamily expressed on activated T cells. CD154 interacts as a costimulatory molecule with CD40 on B Cells to induce B cell activation, resulting in proliferation, immunoglobulin production, and Ig Isotype switching. CD40L also may regulate T cell cytokine production.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Recombinant human CD40L protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Clone W20199I is able to block the binding of clone 24-31 on target cells. Clone W20199I is able to block the binding of CD40 and CD40L interaction on target cells.\u003cbr\u003e\nRRID: AB_3105982 (BioLegend Cat. No. 388203) AB_3105982 (BioLegend Cat. No. 388204)\u003cbr\u003e\nStructure: 32-39 kD type II transmembrane glycoprotein of the TNF superfamily\u003cbr\u003e\nDistribution: Activated T cells\u003cbr\u003e\nFunction: B cell costimulation\u003cbr\u003e\nLigand\/Receptor: CD40\u003cbr\u003e\nCell Type: T cells, Tregs\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: van Kooten C and Banchereau J. 2000. J Leukoc Biol. 67:2-17. Ford GS, et al. 1999. J Immunol. 162:4037-44.\u003cbr\u003e\nGene ID: 959\u003cbr\u003e\nUniProt: View information about CD154 on UniProt.org\u003cbr\u003e\nClone: W20199I\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD40L, TNFSF5, T-BAM, gp39\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866423120041,"sku":"388204","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-388204","provider":"Iright","version":"1.0","type":"link"}