{"product_id":"biolegend-392312","title":"Biolegend, 392312, PE\/Dazzle™ 594 anti-human CD282 (TLR2) Antibody, 100tests","description":"\u003cp\u003eToll-like receptors are type I transmembrane signaling receptors which are critical for the innate host defense to pathogens. Toll-like receptor 2 (TLR2), known as CD282, has been identified as a receptor that is central to the innate immune system's response to lipoproteins of Gram-negative bacteria and Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Full length human TLR2 transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Dazzle™ 594 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * PE\/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2927936 (BioLegend Cat. No. 392311) AB_2927936 (BioLegend Cat. No. 392312)\u003cbr\u003e\nStructure: IL-1R superfamily, TLR family, type 1 transmebrane protein, 90kD\u003cbr\u003e\nDistribution: Monocytes, Granulocytes, endothelial and epithelial cells\u003cbr\u003e\nFunction: Activates innate host defense against bacterial pathogens\u003cbr\u003e\nLigand\/Receptor: Microbial lipoproteins, peptidoglycans, lipoteichoic acid\u003cbr\u003e\nCell Type: Endothelial cells, Epithelial cells, Granulocytes, Monocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Toll Like Receptors\u003cbr\u003e\nAntigen References: 1. Lien E, et al. 1999. J. Biol. Chem. 274:33419. 2. Lien E, et al. 2001. J. Biol. Chem. 276:1873. 3. Sabroe I, et al. 2002. J. Immunol. 168:4701.\u003cbr\u003e\nGene ID: 7097\u003cbr\u003e\nUniProt: View information about CD282 on UniProt.org\u003cbr\u003e\nClone: W15145C\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: TLR2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866299584681,"sku":"392312","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-392312","provider":"Iright","version":"1.0","type":"link"}