{"product_id":"biolegend-399216","title":"Biolegend, 399216, Spark UV™ 387 anti-human CD14 Antibody, 100tests","description":"\u003cp\u003eCD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human CD14\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Spark UV™ 387 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2˚C and 8˚C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * Spark UV™ 387 has a maximum excitation of 351 nm and a maximum emission of 387 nm.\u003cbr\u003e\nExcitation Laser: Ultraviolet Laser (355 nm)\u003cbr\u003e\nRRID: AB_2922626 (BioLegend Cat. No. 399215) AB_2922626 (BioLegend Cat. No. 399216)\u003cbr\u003e\nStructure: GPI-linked membrane glycoprotein, 53-55 kD\u003cbr\u003e\nDistribution: Monocytes, macrophages, granulocytes (low)\u003cbr\u003e\nFunction: LPS receptor, clearance of Gram-negative pathogens\u003cbr\u003e\nInteraction: Monocytes, Macrophages, Granulocytes, Neutrophils\u003cbr\u003e\nLigand\/Receptor: LPS\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Stocks SC, et al. 1990. Biochem. J. 268:275. Wright SD, et al. 1990. Science 4975:1431.\u003cbr\u003e\nGene ID: 929\u003cbr\u003e\nUniProt: View information about CD14 on UniProt.org\u003cbr\u003e\nClone: S18004B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: LPS receptor\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866238865577,"sku":"399216","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-399216","provider":"Iright","version":"1.0","type":"link"}