{"product_id":"biolegend-399302","title":"Biolegend, 399302, Purified anti-human EOS Antibody, 100μg","description":"\u003cp\u003eEOS also known as IKZF4 is an IKAROS Family Member expressed in lymphocytes, specifically in Tregs. It plays an important role in the inhibitory function of Tregs. It may be involved in the development of the central and peripheral nervous systems as well as lymphoid development.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Human EOS recombinant protein (271-520a.a)\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear™ Transcription Factor Staining Protocol. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clones W16032A and W16032B cross-block each other and likely recognize different epitopes.\u003cbr\u003e\nRRID: AB_2832783 (BioLegend Cat. No. 399302)\u003cbr\u003e\nStructure: IKAROS Family Member\u003cbr\u003e\nDistribution: Lymphocytes, specifically in Tregs\u003cbr\u003e\nFunction: Essential for inhibitory function of Tregs\u003cbr\u003e\nInteraction: Binds to 5'GGGAATRCC-3' Ikaros-binding sequence\u003cbr\u003e\nAntigen References: Honma Y, et al. 1999. FEBS Lett. 447(1):76-80. Perdomo J, et al. 2000. J. Biol chem 275(49):38347-54. Westman BJ, et al. 2004. Biochemistry. 43(42):13318-27. Pan F, et al. 2009. Science. 325(5944):1142-6.\u003cbr\u003e\nGene ID: 64375\u003cbr\u003e\nUniProt: View information about EOS on UniProt.org\u003cbr\u003e\nClone: W16032A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Ikaros family zinc finger protein 4 (IKZF4), ZMFN1A4, KIAA1782\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866302271657,"sku":"399302","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-399302","provider":"Iright","version":"1.0","type":"link"}