{"product_id":"biolegend-430508","title":"Biolegend, 430508, LEGEND MAX™ Human IL-6 ELISA Kit, 5precoatedplates","description":"\u003cp\u003eHuman IL-6 (also known as B-cell stimulatory factor 2, Interferon beta-2, Hybrid­oma growth factor, and CTL differentiation factor, etc.) plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, and in hepatocytes it induces acute phase reactants. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes. It has been shown that IL-6 plays a critical role in many physiological and pathological conditions, including autoimmune diseases and rheumatoid arthritis.  BioLegend’s LEGEND MAX™ Human IL-6 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Human IL-6 specific monoclonal antibody is pre-coated on a 96-well strip-well plate.  BioLegend’s LEGEND MAX™ Human IL-6 ELISA Kit is specifically designed for the accurate quantitation of Human IL-6 from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.\u003cbr\u003e\n5precoatedplates\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nApplication: ELISA\u003cbr\u003e\nProduct Citations: Chen J, et al. 2020. Mol Med Rep. 1.144444444. PubMed Liu HW, et al. 2020. Gerontology. 66:562. PubMed Hasebe R, et al. 2022. J Exp Med. 219: . PubMed Wang S, et al. 2022. Adv Sci (Weinh). 9:e2200263. PubMed Zeng W, et al. 2021. Exp Ther Med. 22:1186. PubMed Liang Y, et al. 2018. Oncotarget. 9:14862. PubMed Kusmiwiyati A, et al. 2018. J Taibah Univ Med Sci. 13:129. PubMed Spittaels KJ, et al. 2021. iScience. 24:102575. PubMed Bigenwald C, et al. 2021. Nat Med. 27:851. PubMed Sreenivasan L, et al. 2022. Cells. 11:. PubMed Gholamnezhadjafari R, et al. 2017. Innate Immun. 23:440. PubMed Neidlinger-Wilke C, et al. 2021. Eur Cell Mater. 42:1. PubMed Devadoss D, et al. 2022. iScience. 25:104685. PubMed Hubbard T, et al. 2015. Sci Rep. 5: 12689. PubMed Sreenivasan L, et al. 2020. Cell Death Dis. 1.177083333. PubMed Dudau M, et al. 2021. Front Pharmacol. 12:737571. PubMed Rana T, et al. 2021. PLoS One. 16:e0246393. PubMed Holtkamp C, et al. 2019. PLoS One. 14:e0217269. PubMed\u003cbr\u003e\nSensitivity: 1.6 pg\/mL\u003cbr\u003e\nStandard Range: 7.8-500 pg\/mL\u003cbr\u003e\nCell Sources: T cells, B cells, macrophages, bone marrow stromal cells, fibroblasts, keratinocytes, mesangium, astrocytes, endothelial cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity, Stem Cells\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nGene ID: 3569\u003cbr\u003e\nUniProt: View information about IL-6 on UniProt.org\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-6 Pre-coated ELISA Kit\u003cbr\u003e\nQ: In your LEGEND MAX™ ELISA Kits, there is a step that calls for washing the plates before adding sample. What is the purpose of this step?\u003cbr\u003e\nA: We typically use a stabilizer for pre-coated plates. The additional washing step is designed to remove these components before you start the assay. If you do not perform the washing, the effect on assay performance is negligible.\u003cbr\u003e\nQ: I have multiple LEGEND MAX™ ELISA kits that I want to run simultaneously. Can I use the same wash buffer for all the kits?\u003cbr\u003e\nA: The wash buffer provided in all our LEGEND MAX™ kits is the same and the part numbers on the wash buffer bottles in these kits should be identical. For ELISA MAX™ Deluxe and ELISA MAX™ Standard Sets, we provide a recipe for the wash buffer on each kit’s technical data sheet. This recipe is the same for all ELISA MAX™ sets.\u003cbr\u003e\nQ: For some of your ELISA kits, why do my serum samples require dilution with assay buffer?\u003cbr\u003e\nA: In some cases, dilution with assay buffer is required to minimize the matrix difference between the samples and the standards to achieve better accuracy.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864121397417,"sku":"430508","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-430508","provider":"Iright","version":"1.0","type":"link"}