{"product_id":"biolegend-508701","title":"Biolegend, 508701, Biotin anti-human FGF-basic Antibody, 50μg","description":"\u003cp\u003eFibroblast growth factor-basic (FGF-b, FGF-2) is a heparin-binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. FGF-basic also exerts a potent angiogenic activity in vivo . FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. The JKFb-2 antibody reacts with human fibroblast growth factor - basic (FGF-basic).\u003cbr\u003e\n50μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human bFGF\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.\u003cbr\u003e\nApplication: ELISA Detection\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 1-4 µg\/ml is recommended. To obtain a linear standard curve, serial dilutions of human FGF-basic protein ranging from 500 to 7.8 pg\/ml are recommended for each ELISA plate.It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: ELISA Detection: The biotinylated JKFb-2 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified BHFB15 antibody (Cat. No. 514801\/514802) as the capture antibody.\u003cbr\u003e\nRRID: AB_315527 (BioLegend Cat. No. 508702)\u003cbr\u003e\nStructure: FGF; 17.2 kD (Mammalian)\u003cbr\u003e\nBioactivity: Modulator of cell proliferation, motility, differentiation, angiogenesis; affinity for heparin; associated with ECM\u003cbr\u003e\nCell Sources: Brain, retina, pituitary, kidney, placenta, testis, corpus luteum, adrenal glands, monocytes, prostate, bone, liver, cartilage, endothelial cells, epithelial cells\u003cbr\u003e\nCell Targets: Fibroblasts, myoblasts, osteoblasts, neuronal cells, endothelial cells, keratinocytes, chondrocytes, astrocytes, oligodendrocytes, smooth muscle\u003cbr\u003e\nReceptors: FGFR-1 (flg); FGFR-2 (bek, K-sam); FGFR-4 (flg-2); low affinity coreceptor heparin sulfate and heparin sulfate proteoglycans required for full activity\u003cbr\u003e\nBiology Area: Angiogenesis, Cell Biology, Neuroscience, Synaptic Biology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, Cytokines\/Chemokines, Growth Factors\u003cbr\u003e\nAntigen References: 1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego. 2. Klagsbrun M. 1992. Semin. Cancer Biol. 3:81. 3. Goldfarb M. 1990. Cell Growth Differ. 1:439. 4. Sensenbrenner M. 1993. Prog. Neurobiol. 41:683.\u003cbr\u003e\nRegulation: Released after tissue injuries and during inflammatory processes\u003cbr\u003e\nGene ID: 2247\u003cbr\u003e\nUniProt: View information about FGF-basic on UniProt.org\u003cbr\u003e\nClone: JKFb-2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Fibroblast Growth Factor-basic, bFGF, FGF-2, Heparin-binding growth factor\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: How many biotin molecules are per antibody structure?\u003cbr\u003e\nA: We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866458869929,"sku":"508701","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-508701","provider":"Iright","version":"1.0","type":"link"}