{"product_id":"biolegend-514802","title":"Biolegend, 514802, Purified anti-human FGF-basic Antibody, 500μg","description":"\u003cp\u003eFibroblast growth factor-basic (also known as FGF-b, FGF-2) is a heparin-binding growth factor, which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal, and endothelial cells. FGF-basic also exerts a potent angiogenic activity in vivo . FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. The BHFB15 antibody reacts with human fibroblast growth factor - basic (FGF-basic).\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human FGF-basic.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: ELISA Capture - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration of 2 µg\/ml of the capture antibody was utilized to generate the example standard curve. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: ELISA Capture: The purified BHFB15 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated JKFb-2 antibody as the detecting antibody.\u003cbr\u003e\nRRID: AB_2561316 (BioLegend Cat. No. 514801) AB_2561317 (BioLegend Cat. No. 514802)\u003cbr\u003e\nStructure: 17.2 kD (Mammalian)\u003cbr\u003e\nDistribution: Brain, retina, pituitary, kidney, placenta, testis, corpus luteum, adrenal glands, monocytes, prostate, bone, liver, cartiliage, endothelial cells, and epithelial cells.\u003cbr\u003e\nFunction: Released after tissue injuries and during the inflammatory process.\u003cbr\u003e\nInteraction: Fibroblasts, myobalasts, osteoblasts, neuronal cells, endothelial cells, kerintocytes, chrondrocytes, astrocytes, oligodendrocytes, and the smooth muscle.\u003cbr\u003e\nLigand\/Receptor: FGFR1-1 (flg); FGFR-2 (bek, K-sam); FGFR-4 (flig-2); low affinity coreceptor heparin sulfate, and heparin sulfate proteoglycans required for full activity.\u003cbr\u003e\nCell Type: Monocytes, Epithelial cells, Endothelial cells\u003cbr\u003e\nBiology Area: Angiogenesis, Cell Biology, Immunology, Neuroscience, Synaptic Biology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, Cytokines\/Chemokines, Growth Factors\u003cbr\u003e\nAntigen References: 1. Fitzgerald KA, et al. 2013. The Cytokine Factsbook. Acadmic Press. San Diego. 2. Klagsbrun M, 1992. Semin. Cancer Biol. 3:81. 3. Goldfarb M. 1990. Cell Growth Factor. 1:439. 4. Sensenbrenner M. 1993. Prog. Neurobiol. 6:683.\u003cbr\u003e\nGene ID: 2247\u003cbr\u003e\nUniProt: View information about FGF-basic on UniProt.org\u003cbr\u003e\nClone: BHFB15\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Fibroblast Growth Factor-basic, bFGF, FGF-2, FGF2, Heparin-binding growth factor\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866081022121,"sku":"514802","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-514802","provider":"Iright","version":"1.0","type":"link"}