{"product_id":"biolegend-643902","title":"Biolegend, 643902, Purified anti-Cdk2 Antibody, 100μg","description":"\u003cp\u003eCyclin-dependent kinase 2 (Cdk2), also known as cell division protein kinase 2, is an enzyme involved in cell cycle control. Binding of Cdk2 to Cyclin E in G1 phase is required for G1 to S phase transition, while binding of Cdk2 to Cyclin A is required to progress through the S phase. Clone AN4.3 does not recognize other CDKs.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human, Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: CDK2 recombinant protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Shi L, et al. 2014. J. Immunol. 192:649. PubMed\u003cbr\u003e\nProduct Citations: Cui M, et al. 2024. Oncogene. 2708:43. PubMed Shi L, et al. 2014. J Immunol. 192:649. PubMed\u003cbr\u003e\nRRID: AB_2276103 (BioLegend Cat. No. 643901)\u003cbr\u003e\nStructure: There are two isoforms reported in human with predicted MW of 30 kD, 34 kD, respectively; there are also two isoforms reported in mouse with predicted MW of 34 kD, 39 kD, respectively.\u003cbr\u003e\nDistribution: Nuclear protein, predicted molecular weight 34 kD.\u003cbr\u003e\nFunction: Involved in the control of the cell cycle\u003cbr\u003e\nInteraction: Cyclins A, B1, B3, D, or E.\u003cbr\u003e\nBiology Area: Cell Biology, Cell Cycle\/DNA Replication\u003cbr\u003e\nAntigen References: 1. Jeffrey PD, et al. 1995. Nature 376:313\u003cbr\u003e\nGene ID: 1017\u003cbr\u003e\nUniProt: View information about Cdk2 on UniProt.org\u003cbr\u003e\nClone: AN4.3\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: p33(CDK2)\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862540177577,"sku":"643902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-643902","provider":"Iright","version":"1.0","type":"link"}