{"product_id":"biolegend-847002","title":"Biolegend, 847002, Purified anti-CD66e Antibody, 100μg","description":"\u003cp\u003eCarcinoembryonic antigen (CEA), also known as CD66e, is a glycoprotein involved in cell adhesion and intracellular signaling. It is normally produced during fetal development in the gut, and its production stops before birth. CEA is re-expressed in increased amounts in Intestinal Carcinomas and several other tumors.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Recombinant human CEA.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: IHC-P - Quality testedIHC-F, WB - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 1.0 µg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2629664 (BioLegend Cat. No. 847002)\u003cbr\u003e\nStructure: CEA is a 702 amino acid protein with a molecular mass of 77 kD.\u003cbr\u003e\nDistribution: Tissue distribution: intestine, colon, and blood. Cellular distribution: extracellular and plasma membrane.\u003cbr\u003e\nFunction: CEA is a biomarker for gastrointestinal cancers and may promote tumor development through its role as an adhesion molecule.\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology\u003cbr\u003e\nAntigen References: 1. Go VL. 1976. Cancer. 37:562. PubMed 2. DeLellis RA, et al. 1978. Am. J. Clin. Pathol. 70:587. PubMed 3. Kamino H, et al. 1988. Cancer. 61:1142. PubMed 4. Tron V, et al. 1987. Arch. Pathol. Lab. Med. 111:291. PubMed\u003cbr\u003e\nGene ID: 1048\u003cbr\u003e\nUniProt: View information about CD66e on UniProt.org\u003cbr\u003e\nClone: BSB-13\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Carcinoembryonic antigen, CEA, CEACAM5, CD66 antigen, CD66e\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862917075113,"sku":"847002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-847002","provider":"Iright","version":"1.0","type":"link"}