{"product_id":"biolegend-863501","title":"Biolegend, 863501, Purified anti-ADH1 Antibody, 25μg","description":"\u003cp\u003eADH1 is the γ subunit of class I alcohol dehydrogenase. The alcohol dedydrogenase family is involved in metabolization of a variety of substrates, including ethanol and lipid peroxidation products. ADH1 is related to the signaling pathway of cytochrome P450 metabolism. It is also associated with several diseases including late-onset Parkinson Disease.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human, Mouse, Rat\u003cbr\u003e\nAntibody Type: Polyclonal\u003cbr\u003e\nHost Species: Rabbit\u003cbr\u003e\nImmunogen: Recombinant Alcohol Dehydrogenase 1 (ADH1) expressed in E.coli.\u003cbr\u003e\nFormulation: 0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: Store at 4°C for up to 3 months. For longer term storage, aliquot into small volumes and store at -20°C.\u003cbr\u003e\nApplication: WB - Quality testedIHC-P - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 µg\/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2820148 (BioLegend Cat. No. 863501)\u003cbr\u003e\nStructure: ADH1 is a 375 amino acid protein with an apparent molecular mass of ~39 kD.\u003cbr\u003e\nDistribution: Tissue Distribution: Liver, kidney, pancreas, and gallbladder Cellular Distribution: Cytosol and nucleus\u003cbr\u003e\nFunction: ADH1 is involved in ethanol and hydroxysteroids metabolism.\u003cbr\u003e\nInteraction: Ethanol, retinol, hydroxysteroids\u003cbr\u003e\nCell Type: Mesenchymal cells\u003cbr\u003e\nBiology Area: Cell Biology, Neurodegeneration, Neuroscience\u003cbr\u003e\nMolecular Family: Aldehyde Dehydrogenases\u003cbr\u003e\nAntigen References: Lieber CS. 2004. Alcohol. 34(1):9-19. Zuo L, et al. 2013. Hum Genet. 132(7):735-43. Dumont S, et al. 2018. PLoS One. 13(9):e0204530.\u003cbr\u003e\nGene ID: 1261152224172\u003cbr\u003e\nUniProt: View information about ADH1 on UniProt.org\u003cbr\u003e\nClone: Poly28635\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: ADH1, Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide, Alcohol Dehydrogenase Subunit Gamma, Aldehyde Reductase, EC 1.1.1\u003cbr\u003e\nIsotype: Rabbit Polyclonal IgG\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866466635945,"sku":"863501","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-863501","provider":"Iright","version":"1.0","type":"link"}