{"product_id":"biolegend-932302","title":"Biolegend, 932302, Purified anti-Hepatitis B Surface Antigen (HBsAg) Antibody, 100μg","description":"\u003cp\u003eHepatitis B is a liver infection caused by the Hepatitis B virus (HBV). Hepatitis B surface antigen (HBsAg) contains the large (L), middle (M), and small (S) surface proteins of HBV. HBsAg can be detected at high levels in serum during acute or chronic HBV infection. The body normally produces antibodies to HBsAg as part of the normal immune response to infection. HBsAg is the antigen used to make the HBV vaccine and is also a diagnostic marker.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Hepatatis B virus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Purified HBsAg from human HBsAg-positive serum.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: IHC-P - Quality tested WB - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Huang T, et al. 2005. J. Biol. Chem. 280:27742. (WB) Wang H, et al. 2003. Am. J. Pathol. 163:2441. (WB) Shih H, et al. 2008. J. Virol. 82:2250. (WB) Shih H, et al. 2012. J. Virol. 86:9044. (WB) Hsu S, et al. 2004. J. Virol. 78:6. (WB)\u003cbr\u003e\nProduct Citations: Giadans CG, et al. 2019. J Viral Hepat. 26:727. PubMed Biswas S, et al. 2022. Nat Commun. 13:2995. PubMed\u003cbr\u003e\nRRID: AB_2566428 (BioLegend Cat. No. 932302)\u003cbr\u003e\nStructure: Hepatitis B surface antigen (HBsAg) contains the large (L), middle (M), and small (S) surface proteins of Hepatitis B virus (HBV).\u003cbr\u003e\nDistribution: HBsAg is on the surface of HBV that is present in bodily fluids and hepatocytes of infected individuals.\u003cbr\u003e\nFunction: HBsAg plays a key role in HBV's infection of hepatocytic cells.\u003cbr\u003e\nInteraction: Hepatocytes.\u003cbr\u003e\nLigand\/Receptor: Several hepatocytic receptors including asialoglycoprotein receptors and Annexin V.\u003cbr\u003e\nBiology Area: Cell Biology\u003cbr\u003e\nAntigen References: 1. Toita B, et al. 2015. World J. Gastroenterol. 24:7400-7411.\u003cbr\u003e\nGene ID: 944569\u003cbr\u003e\nUniProt: View information about HBsAg on UniProt.org\u003cbr\u003e\nClone: A10F1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: HBsAg, Major surface protein, Large S protein, Hepatitis B Surface Antigen, ayw subtype, Australian antigen\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862517764265,"sku":"932302","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/biolegend-932302","provider":"Iright","version":"1.0","type":"link"}