CST, 10333S, CAPZB (E4H6C) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying CAPZB. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CAPZB (E4H6C) Rabbit Monoclonal Antibody (CST #10333) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity CAPZB (E4H6C) Rabbit Monoclonal Antibody recognizes endogenous levels of total CAPZB protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile21 of human CAPZB protein. Background F-actin-capping protein, a ubiquitously expressed heterodimer composed of structurally similar α and β subunits, regulates cytoskeletal organization and function by binding to the actin filament barbed ends and maintaining the cellular pool of monomeric actin (1). CAPZB expression is associated with tumor progression in epithelioid sarcoma (EpiS), regulating tumor cell growth, invasion, and migration (2).  Alternate Names Cap Z; CAPB; CAPPB; capping actin protein of muscle Z-line beta subunit; capping actin protein of muscle Z-line subunit beta; capping protein (actin filament) muscle Z-line, beta; CAPZ; CapZ beta; CAPZB; epididymis secretory sperm binding protein; F-actin capping protein beta subunit; F-actin-capping protein subunit beta; MGC104401; MGC129749; MGC129750 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 30 Source/Isotype: Rabbit IgG