{"product_id":"cst-10333t","title":"CST,  10333T, CAPZB (E4H6C) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying CAPZB. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CAPZB (E4H6C) Rabbit Monoclonal Antibody (CST #10333) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nCAPZB (E4H6C) Rabbit Monoclonal Antibody recognizes endogenous levels of total CAPZB protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile21 of human CAPZB protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nF-actin-capping protein, a ubiquitously expressed heterodimer composed of structurally similar α and β subunits, regulates cytoskeletal organization and function by binding to the actin filament barbed ends and maintaining the cellular pool of monomeric actin (1). CAPZB expression is associated with tumor progression in epithelioid sarcoma (EpiS), regulating tumor cell growth, invasion, and migration (2). Â\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCap Z; CAPB; CAPPB; capping actin protein of muscle Z-line beta subunit; capping actin protein of muscle Z-line subunit beta; capping protein (actin filament) muscle Z-line, beta; CAPZ; CapZ beta; CAPZB; epididymis secretory sperm binding protein; F-actin capping protein beta subunit; F-actin-capping protein subunit beta; MGC104401; MGC129749; MGC129750\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 30\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797536362665,"sku":"10333T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-10333t","provider":"Iright","version":"1.0","type":"link"}