{"product_id":"cst-10691t","title":"CST,  10691T, ADA2B (F6G5T) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying ADA2B. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, ADA2B (F6G5T) Rabbit Monoclonal Antibody (CST #10691) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nADA2B (F6G5T) Rabbit Monoclonal Antibody recognizes endogenous levels of total ADA2B protein. This antibody does not cross-react with ADA2A protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp172 of human ADA2B protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nADA2A and ADA2B are human homologs of the yeast SAGA complex member Ada2. While highly related, ADA2A and B appear functionally distinct. ADA2A is incorporated into PCAF-containing complexes, while ADA2B is recruited to SAGA complexes with GCN5 and Brg1 (1-3). ADA2 proteins form a trimer with GCN5L and ADA3, and enhance GCN5L acetyltransferase activity (4,5). The C-terminal domain of ADA2A and ADA2B determines incorporation into their various complexes, resulting in specific targeting toward histone H3 or H4 (6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nADA2-beta; ADA2-like protein beta; ADA2(beta); ADA2B; MGC21874; TAD2B; TADA2B; Transcriptional adapter 2-beta; transcriptional adaptor 2 (ADA2 homolog, yeast)-beta; transcriptional adaptor 2B\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 55\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797545111721,"sku":"10691T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-10691t","provider":"Iright","version":"1.0","type":"link"}