{"product_id":"cst-12288s","title":"CST,  12288S, Protor-2 (D19A5) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Protor2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Protor-2 (D19A5) Rabbit Monoclonal Antibody (CST #12288) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nProtor-2 (D19A5) Rabbit Monoclonal Antibody recognizes endogenous levels of total protor-2 protein.\nSpecies Reactivity: Human, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human protor-2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nProtein observed with rictor-1 (protor-1) and protor-2 both interact with rictor and were identified as components of mTORC2 (1). The absence of protor-1 or protor-2 does not affect the assembly of other mTORC2 components into an active complex (2). Protor-1 was shown to be essential for the activation of SGK1 mediated by mTORC2 (2). Protor-2 plays a role in tristetraprolin-mediated mRNA turnover (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ14213; FLJ22630; MGC16218; proline rich 5 like; Proline-rich protein 5-like; Protein observed with Rictor-2; Protor-2; PROTOR2; PRR5L\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H Mk\nSENSITIVITY: Endogenous\nMW (kDa): 42\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797569392809,"sku":"12288S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-12288s","provider":"Iright","version":"1.0","type":"link"}