{"product_id":"cst-12479s","title":"CST,  12479S, PANK2 (D11E2) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying PANK2 mouse. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, PANK2 (D11E2) Rabbit Monoclonal Antibody (CST #12479) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nPANK2 (D11E2) Rabbit Monoclonal Antibody recognizes endogenous levels of total PANK2 protein.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu76 of mouse PANK2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nPantothenate kinase 2 (PANK2) catalyzes the first step in coenzyme A (CoA) biosynthesis (1,2). Human PANK2 protein is located in the mitochondria, and research studies have shown some mutations in human are linked to neurodegeneration (2). Alternatively, mouse PANK2 protein localizes in the cytosol, and defective PANK2 protein in mice leads to retinal degeneration (1,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n4933409I19Rik; AI642621; MGC118448; OTTMUSP00000017161; Pank2; Pantothenate kinase 2; pantothenate kinase 2 (Hallervorden-Spatz syndrome); Pantothenate kinase 2, mitochondrial\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Endogenous\nMW (kDa): 49\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46801045815465,"sku":"12479S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-12479s","provider":"Iright","version":"1.0","type":"link"}