{"product_id":"cst-13036s","title":"CST,  13036S, NKG7 (F4V5I) Rabbit Monoclonal Antibody (Alexa Fluor® 555 Conjugate)","description":"Monoclonal Antibody for studying NKG7. Validated for Immunohistochemistry (Paraffin). Highly specific and rigorously validated in-house, NKG7 (F4V5I) Rabbit Monoclonal Antibody (Alexa Fluor\u003csup\u003e®\u003c\/sup\u003e 555 Conjugate) (CST #13036) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nImmunohistochemistry (Paraffin): 1:50 - 1:200\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg\/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNKG7 (F4V5I) Rabbit Monoclonal Antibody (Alexa Fluor\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly161 of human NKG7 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNatural killer cell granule protein 7 (NKG7, also known as GMP-17 and GIG-I) is a novel type 1 integral membrane protein expressed at high levels in lymphocytes, including natural killer (NK) cells, γδ T cells, a subset of αβ T cells, lymphokine-activated killer (LAK) cells (1), and activated T regulatory cells (2). NKG7 expression can be induced in neutrophils following GM-CSF treatment (3). NKG7 protein is localized to the membranes of cytotoxic granules. Following target cell-induced NK cell degranulation, NKG7 translocates from granules to the plasma membrane (4). Studies have also shown that NKG7 is significantly upregulated in allograft rejection patients (5-8).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nG-CSF-induced gene 1 protein; GIG-1 protein; GIG1; GMP-17; granule membrane protein 17; Granule membrane protein of 17 kDa; natural killer cell granule protein 7; natural killer cell group 7 sequence; Natural killer cell protein 7; NKG7; p15-TIA-1; Protein NKG7; Q16617\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800339108009,"sku":"13036S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-13036s","provider":"Iright","version":"1.0","type":"link"}