{"product_id":"cst-13140s","title":"CST,  13140S, LAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying C7orf59. Validated for WB,IP,IHC,IF. Available in 2 sizes. Highly specific and rigorously validated in-house, LAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody (CST #13140) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunohistochemistry (Paraffin): 1:1000\nImmunofluorescence (Immunocytochemistry): 1:1600\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 38635 .\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence (Immunocytochemistry)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nLAMTOR4\/C7orf59 (D4P6O) Rabbit Monoclonal Antibody recognizes endogenous levels of total LAMTOR4 (C7orf59) protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human LAMTOR4 (C7orf59) protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nLate endosomal\/lysosomal adaptor and MAPK and MTOR activator 4 (LAMTOR4) is an essential component of the ragulator protein complex that is encoded by the gene (1). The ragulator complex also includes LAMTOR1\/C11orf59, LAMTOR2\/ROBLD3, LAMTOR3\/MAPKSP1, and HBXIP (1,2). This pentameric protein complex localizes to the lysosomal membrane and is essential for the lysosomal localization of Rag GTPases and mTORC1 as well as the subsequent activation of mTORC1 in response to amino acid signaling (1-3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nC7orf59; LAMTOR4; Late endosomal\/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal\/lysosomal adaptor, MAPK and MTOR activator 4; LOC389541; LTOR4; Ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; UPF0539 protein C7orf59\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 11\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797588168873,"sku":"13140S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-13140s","provider":"Iright","version":"1.0","type":"link"}