{"product_id":"cst-13144t","title":"CST,  13144T, Neurogenin 2 (D2R3D) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying neurogenin 2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Neurogenin 2 (D2R3D) Rabbit Monoclonal Antibody (CST #13144) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNeurogenin 2 (D2R3D) Rabbit Monoclonal Antibody recognizes endogenous levels of total neurogenin 2 protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human neurogenin 2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNeurogenin 2 (Ngn2, NeuroG2) is a proneural, basic helix-loop-helix transcription (bHLH) factor and member of the neurogenin family that includes neurogenin 1 and neurogenin 3 (1). Neurogenin 2 is expressed in neuronal progenitor cells, is required for generation of glutamatergic neurons and is commonly used as a marker of neuronal differentiation (2,3). Neurogenin 2 upregulates a number of targets including the bHLH transcription factor NeuroD (4). Phosphorylation of Ngn2 at Tyr241 controls migration and dendritic morphology of cortical neurons (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nATOH4; BHLHA8; Class A basic helix-loop-helix protein 8; Math4A; MGC46562; NEUROG2; neurogenin 2; Neurogenin-2; NGN-2; NGN2; Protein atonal homolog 4\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 35\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797588332713,"sku":"13144T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-13144t","provider":"Iright","version":"1.0","type":"link"}