{"product_id":"cst-13894t","title":"CST,  13894T, eIF5 (D5G9) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying eIF5. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, eIF5 (D5G9) Rabbit Monoclonal Antibody (CST #13894) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\neIF5 (D5G9) Rabbit Monoclonal Antibody recognizes endogenous levels of total eIF5 protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human eIF5 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nEukaryotic translation initiation factor 5 (eIF5) is crucial for the assembly of translation initiation complex and plays an important role in protein synthesis (1). eIF5 interacts with the 43S initiation complex to stimulate hydrolysis of GTP bound to eIF2 (1-3). Studies suggest that eIF5 functions as the GTPase-activating protein (GAP) in the hydrolysis of GTP-bound eIF2 (4,5). This hydrolysis leads to the release of initiation factors from the 40S ribosomal subunit, which is a necessary step in the formation of the 80S initiation complex (1).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\neIF-5; EIF-5A; EIF5; Eukaryotic translation initiation factor 5; IF5\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 58\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797601702057,"sku":"13894T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-13894t","provider":"Iright","version":"1.0","type":"link"}