{"product_id":"cst-15356t","title":"CST,  15356T, NSDHL (F3P8W) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying NSDHL. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, NSDHL (F3P8W) Rabbit Monoclonal Antibody (CST #15356) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nNSDHL (F3P8W) Rabbit Monoclonal Antibody recognizes endogenous levels of total NSDHL protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human NSDHL protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nNAD(P) dependent steroid dehydrogenase-like (NSDHL) is an enzyme involved in the late stages of cholesterol biosynthesis (1). Mutations in the gene are associated with the X-linked conditions CHILD (congenital hemidysplasia with ichthyosiform erythroderma and limb defects) and CK syndromes (2,3). Elevated NSDHL expression has been found in several cancer types, including breast, gastric, pancreatic, and multiple myeloma, and can be a potent driver of metastasis and predictor of poor prognosis (4-8). Â\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nepididymis secretory sperm binding protein; H105E3; NAD(P) dependent steroid dehydrogenase-like; NAD(P) dependent steroid dehydrogenase-like protein transcript; NSDHL; Protein H105e3; SDR31E1; short chain dehydrogenase\/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; XAP104\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 40\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797625753769,"sku":"15356T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-15356t","provider":"Iright","version":"1.0","type":"link"}