{"product_id":"cst-16431t","title":"CST,  16431T, BCAT1 (D4V2T) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying BCAT1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, BCAT1 (D4V2T) Rabbit Monoclonal Antibody (CST #16431) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nBCAT1 (D4V2T) Rabbit Monoclonal Antibody recognizes endogenous levels of total BCAT1 protein. This antibody does not cross-react with BCAT2 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human BCAT1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nBCAT1 and BCAT2 are cytosolic and mitochondrial branched chain aminotransferases, respectively (1,2). Research studies have implicated BCAT1 in distant metastasis in patients with advanced colorectal cancer (3). Disruption of BCAT2 in mice leads to higher levels of plasma branched-chain amino acids, reduced adiposity and body weight, and increased energy expenditure, suggesting its role in regulating insulin sensitivity (4).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nBCAT(c); BCAT1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; DKFZp686E12175; ECA39; MECA39; placental protein 18; PNAS-121; PNAS121; PP18; Protein ECA39\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 43\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797629784233,"sku":"16431T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-16431t","provider":"Iright","version":"1.0","type":"link"}