{"product_id":"cst-16847s","title":"CST,  16847S, PYURF (F9F4X) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying PYURF. Validated for Western Blotting,Simple Western™,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, PYURF (F9F4X) Rabbit Monoclonal Antibody (CST #16847) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nSimple Western™: 1:50 - 1:250\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nPYURF (F9F4X) Rabbit Monoclonal Antibody recognizes endogenous levels of total PYURF protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala71 of human PYURF protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nupstream open reading frame (PYURF) is a mitochondrial S-adenosylmethionine-dependent methyltransferase chaperone. This protein supports the assembly of complex I in the electron transport chain and coenzyme Q biosynthesis (1). In addition, was also shown to be required for oxidative phosphorylation. Disruption of gene expression results in isolated complex I deficiency (2). Furthermore, PYURF is suggested to be a potential subunit of the NDUFAF5 hydroxylase complex (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nMGC14156; OTTHUMP00000161562; phosphatidylinositol glycan anchor biosynthesis, class Y; phosphatidylinositol glycan, class Y; phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; phosphatidylinositol-glycan biosynthesis class Y protein; PIG-Y; PIGY; PIGY upstream reading frame; PIGY upstream reading frame protein; PREY; Protein preY, mitochondrial; PYURF\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 13\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797631586473,"sku":"16847S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-16847s","provider":"Iright","version":"1.0","type":"link"}