{"product_id":"cst-19766s","title":"CST,  19766S, Ferrostatin-1","description":"Chemical Modulators for studying in the research area.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nFerrostatin-1 is supplied as a lyophilized powder. For a 15 mM stock, reconstitute 5 mg of powder in 1.27 mL of DMSO. Working concentrations and length of treatment can vary depending on the desired effect.\n\u003cb\u003eStorage\u003c\/b\u003e\nStore lyophilized at ambient temperature, desiccated. In lyophilized form, the chemical is stable for 24 months. Once in solution, store at -20ºC and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze\/thaw cycles.\n\u003cb\u003eBackground\u003c\/b\u003e\nFerrostatin-1 is an antioxidant that is a potent, selective inhibitor of erastin-induced ferroptosis with an EC value of 60 nM (1,2). It effectively inhibits ferroptosis in cancer cells and prevents glutamate-induced cell death in rat hippocampal brain slices. In disease models, it has been shown to inhibit production of reactive oxygen species (ROS) and depletion of membrane lipids (1). Ferrostatin-1 has been shown to inhibit cell death in cell models of Huntington's disease, periventricular leukomalacia, and kidney dysfunction (1,2).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nEthyl 3-amino-4-(cyclohexylamino)benzoate","brand":"CST","offers":[{"title":"Default Title","offer_id":46800693100713,"sku":"19766S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-19766s","provider":"Iright","version":"1.0","type":"link"}