{"product_id":"cst-20026s","title":"CST,  20026S, XRCC3 (E9X4D) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying XRCC3. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, XRCC3 (E9X4D) Rabbit Monoclonal Antibody (CST #20026) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nXRCC3 (E9X4D) Rabbit Monoclonal Antibody recognizes endogenous levels of total XRCC3 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val280 of human XRCC3 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nXRCC3 (X-ray repair cross-complementing protein 3) is one of five RAD51 paralogs that form two distinct complexes, BCDX2 (RAD51B, RAD51C, RAD51D, and XRCC2) and CX3 (RAD51C and XRCC3) (1). Along with RAD51, these complexes are crucial in the repair of DNA double-strand breaks through homologous recombination (2), and in the response to DNA replication stress (3,4). The CX3 complex also plays a role in maintaining mitochondrial DNA integrity during replicative stress (5). XRCC3 genetic polymorphisms are associated with risk and prognosis in human cancer (6-9).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCMM6; DNA repair protein XRCC3; RAD51-like; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross complementing 3; X-ray repair cross complementing protein 3; X-ray repair cross-complementing protein 3; XRCC3\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 40\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797643350185,"sku":"20026S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-20026s","provider":"Iright","version":"1.0","type":"link"}