{"product_id":"cst-20379s","title":"CST,  20379S, FcR gamma Antibody","description":"Polyclonal Antibody for studying FcER1G. Validated for Western Blotting. Highly specific and rigorously validated in-house, FcR gamma Antibody (CST #20379) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nFcR gamma Antibody recognizes endogenous levels of total FcRγ protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human FcRγ protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nFcRγ (Fc receptor gamma-chain, FcεRI gamma, High affinity immunoglobulin epsilon receptor subunit gamma) is a component of the IgE Fc receptor FcεRI, a tetramer of an alpha chain, a beta chain, and two disulfide-linked gamma chains (FcRγ) (1,2). FcεRI is expressed exclusively on basophils and mast cells and is involved in triggering allergic reactions (1-3). FcRγ also forms signaling complexes with other Fc receptors, including FcγRIA and FcγRIIIA. FcRγ shows high homology to the T cell receptor (TCR) ζ chain (4-6) and contains an immunoreceptor tyrosine-based activation motif (ITAM) which elicits a pro-inflammatory response (1-3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFc epsilon receptor Ig; Fc fragment of IgE receptor Ig; Fc fragment of IgE, high affinity I, receptor for; Fc receptor gamma-chain; Fc-epsilon RI-gamma; FCER1G; FCERG; FceRI gamma; FCRG; FcRgamma; gamma polypeptide; High affinity immunoglobulin epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; immunoglobulin E receptor, high affinity, gamma chain\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 12\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46797650755753,"sku":"20379S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-20379s","provider":"Iright","version":"1.0","type":"link"}