{"product_id":"cst-20418v1","title":"CST,  20418V1, PathScan® RP G4S Linker\/CD3 zeta CAR Sandwich ELISA Kit","description":"ELISA Kit for studying in the research area.\n\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: ELISA+\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nThe PathScan\nSpecies Reactivity: All Species Expected\n\u003cb\u003eBackground\u003c\/b\u003e\nThe poly-Glycine-Serine (G4S) linker is a type of flexible, unstructured synthetic peptide linker sequence often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The linker itself consists of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser, that is repeated and commonly found as either a 15-mer (G4S) or 20-mer (G4S) within scFv-based CARs and scFv fragments. The linker sequence length plays a role in controlling scFv stability and the noncovalent association between the VH and VL domains (1,2).\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: All","brand":"CST","offers":[{"title":"Default Title","offer_id":46800583721129,"sku":"20418V1","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-20418v1","provider":"Iright","version":"1.0","type":"link"}