CST, 2164T, EB-1 (1A11/4) Mouse Monoclonal Antibody

Monoclonal Antibody for studying EB1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, EB-1 (1A11/4) Mouse Monoclonal Antibody (CST #2164) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:100 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity EB-1 (1A11/4) Mouse Monoclonal Antibody detects endogenous levels of EB-1. Species Reactivity: Human, Monkey Source / Purification Monoclonal antibody is produced by immunizing CD-1 mice with a recombinant human EB-1 protein. Background EB1 (end-binding protein 1) is a microtubule associated protein (1). EB1 localizes to the growing ends of microtubules, the centrosome and the mitotic spindle (2-4). EB1 is also found to associate with the adenomatous polyposis coli (APC) protein (5). Recent studies also suggest that EB1 plays a role in microtubule-based transport (2). Alternate Names adenomatous polyposis coli-binding protein EB1; APC-binding protein EB1; EB1; End-binding protein 1; MAPRE1; MARE1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein, RP/EB family, member 1 Specification REACTIVITY: H Mk SENSITIVITY: Endogenous MW (kDa): 30 Source/Isotype: Mouse IgG2b