{"product_id":"cst-2167s","title":"CST,  2167S, Rab4 Antibody","description":"Polyclonal Antibody for studying Rab4. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Rab4 Antibody (CST #2167) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nRab4 Antibody detects endogenous levels of total Rab4 protein.\nSpecies Reactivity: Human, Mouse, Rat, Hamster, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp128 of human Rab4 protein. Antibodies are purified by protein A and peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nRab4 is a member of the Ras superfamily of small Rab GTPases implicated in endocytosis. Rab4 is localized at early endosomes\/recycling endosomes and functions as a key regulator for sorting\/recycling of membrane and proteins (1,2). Rab4 has two isoforms, Rab4A and Rab4B, both of which are localized in similar cellular compartments and are believed to have similar functions (4). Rab4 interacts with several Rab4 effectors in a complex on a special endosome site that promotes membrane\/protein recycling (1,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nHRES-1; HRES-1\/RAB4; HRES1; HTLV-1 related endogenous sequence; Oncogene RAB4; RAB4; RAB4, member RAS oncogene family; RAB4A; RAB4A, member RAS oncogene family; Ras-related protein Rab-4A\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Hm Mk\nSENSITIVITY: Endogenous\nMW (kDa): 25\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46797658095785,"sku":"2167S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-2167s","provider":"Iright","version":"1.0","type":"link"}