{"product_id":"cst-23408s","title":"CST,  23408S, ACAA2 (F4Y9U) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MKT\/ACAA2. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, ACAA2 (F4Y9U) Rabbit Monoclonal Antibody (CST #23408) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nSimple Western™: 1:10 - 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nACAA2 (F4Y9U) Rabbit Monoclonal Antibody recognizes endogenous levels of total ACAA2 protein. This antibody does not cross-react with ACAA1 protein.\nSpecies Reactivity: Human, Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val219 of human ACAA2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nAcetyl-CoA acyltransferase 2 (ACAA2), also known as medium-chain 3-ketoacyl-CoA thiolase, is a mitochondrial enzyme that participates in the catalyzation of the last step in the fatty acid β-oxidation pathway (1,2). Studies identified a short-chain carbon circuit at the C4 node of fatty acid oxidation (FAO) where reverse flux of acetyl-CoA derived from pyruvate through ACAA2 produces free CoA and NAD , therefore promoting lipid tolerance and redox stability in heart mitochondria (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n3-ketoacyl-CoA thiolase, mitochondrial; ACAA2; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; acetyl-CoA acyltransferase 2; acetyl-Coenzyme A acyltransferase 2; Acyl-CoA hydrolase, mitochondrial; beta ketothiolase; Beta-ketothiolase; DSAEC; FLJ35992; FLJ95265; Mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; T1; THIM\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M\nSENSITIVITY: Endogenous\nMW (kDa): 42\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46797666386089,"sku":"23408S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-23408s","provider":"Iright","version":"1.0","type":"link"}