{"product_id":"cst-2642s","title":"CST,  2642S, alpha-Synuclein Antibody","description":"Polyclonal Antibody for studying Synuclein-alpha. Validated for Western Blotting,Immunoprecipitation. Highly specific and rigorously validated in-house, alpha-Synuclein Antibody (CST #2642) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nalpha-Synuclein Antibody detects the alpha isoform of synuclein. This antibody may cross-react with β-synuclein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy-terminal sequence of human α-synuclein. Antibodies are purified by protein A and peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nα-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinson's disease (1).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAlpha-synuclein; alpha-synuclein, isoform NACP140; I+\/--synuclein; MGC110988; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; SNCA; synuclein alpha; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); SYUA; truncated alpha synuclein\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 18\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46797937868969,"sku":"2642S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-2642s","provider":"Iright","version":"1.0","type":"link"}