{"product_id":"cst-2647t","title":"CST,  2647T, alpha-Synuclein (Syn204) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying Synuclein-alpha. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, alpha-Synuclein (Syn204) Mouse Monoclonal Antibody (CST #2647) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nalpha-Synuclein (Syn204) Mouse Monoclonal Antibody detects endogenous levels of total synuclein protein. This antibody detects recombinant Î± but not Î²-synuclein (Giasson, B.I. et al., 2000).\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a recombinant human Î±-synuclein protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nÎ±-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. Î±-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the Î±-Synuclein gene are linked to Parkinson's disease (1).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nAlpha-synuclein; alpha-synuclein, isoform NACP140; I+\/--synuclein; MGC110988; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; SNCA; synuclein alpha; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); SYUA; truncated alpha synuclein\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 18\nSource\/Isotype: Mouse IgG2a","brand":"CST","offers":[{"title":"Default Title","offer_id":46797938262185,"sku":"2647T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-2647t","provider":"Iright","version":"1.0","type":"link"}