{"product_id":"cst-2721t","title":"CST,  2721T, Wnt3a (C64F2) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying Wnt3a. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, Wnt3a (C64F2) Rabbit Monoclonal Antibody (CST #2721) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nWnt3a (C64F2) Rabbit Monoclonal Antibody detects transfected Wnt3a protein in L cells and the conditioned medium from L\/Wnt3a cells.\nSpecies Reactivity: Mouse\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu256 of human Wnt3a.\n\u003cb\u003eBackground\u003c\/b\u003e\nThe Wnt family includes several secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt\/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nMGC119418; MGC119419; MGC119420; Protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt family member 3A; WNT3A\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: M\nSENSITIVITY: Transfected Only\nMW (kDa): 42\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800085745833,"sku":"2721T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-2721t","provider":"Iright","version":"1.0","type":"link"}