{"product_id":"cst-28569t","title":"CST,  28569T, MFSD1 (F2B4C) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying MFSD1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, MFSD1 (F2B4C) Rabbit Monoclonal Antibody (CST #28569) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMFSD1 (F2B4C) Rabbit Monoclonal Antibody recognizes endogenous levels of total MFSD1 protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MFSD1 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nMajor facilitator superfamily domain-containing protein 1 (MFSD1) is a member of the solute carrier (SLC) superfamily that functions as a lysosomal dipeptide exporter (1-3). It forms a heterodimeric complex with glycosylated lysosomal membrane protein (GLMP) that functions as a critical accessory subunit for MFSD1 (3). Â knockout mice develop splenomegaly and severe liver disease, phenotypes that are mimicked in knockouts (4). In tumor models, loss of enables high levels of invasion and metastasis (5). MFSD1 is expressed in the TFEB gene network regulating lysosomal biogenesis and function (6).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nFLJ14153; major facilitator superfamily domain containing 1; Major facilitator superfamily domain-containing protein 1; MFSD1; Minerva; SMAP-4; SMAP4; Smooth muscle cell-associated protein 4\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 35\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46798055145641,"sku":"28569T","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-28569t","provider":"Iright","version":"1.0","type":"link"}