{"product_id":"cst-29256s","title":"CST,  29256S, AMACR (F7T6V) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying AMACR. Validated for Western Blotting,Immunoprecipitation,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, AMACR (F7T6V) Rabbit Monoclonal Antibody (CST #29256) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:200\nImmunohistochemistry (Paraffin): 1:400 - 1:1600\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunohistochemistry (Paraffin)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nAMACR (F7T6V) Rabbit Monoclonal Antibody recognizes endogenous levels of total AMACR protein. Non-specific diffuse staining was observed in human skeletal muscle, breast myoepithelium, and scattered cells in thymus by immunohistochemistry.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human AMACR protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nα-Methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives (1). AMACR has been reported to be a biomarker for prostate cancer (2-4). AMACR expression is also related to other types of cancers, such as hepatocellular carcinoma (1), noninvasive bladder cancer (5), colorectal cancer (6), and gastric adenocarcinoma (7).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\n2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; AMACR; AMACRD; CBAS4; P504S; RACE; RM\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 42\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46798059634857,"sku":"29256S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-29256s","provider":"Iright","version":"1.0","type":"link"}