{"product_id":"cst-32790s","title":"CST,  32790S, HMOX2\/HO-2 (D9J9U) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying HMOX2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, HMOX2\/HO-2 (D9J9U) Rabbit Monoclonal Antibody (CST #32790) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nHMOX2\/HO-2 (D9J9U) Rabbit Monoclonal Antibody recognizes endogenous levels of total HMOX2\/HO-2 protein.\nSpecies Reactivity: Human, Mouse, Rat, Hamster, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala131 of human HMOX2\/HO-2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nHeme oxygenases (HMOX or HO) catalyze the rate-limiting step of the oxidative degradation of heme into iron, carbon monoxide, and biliverdin (1). Biliverdin is then converted to bilirubin (2). Heme is a strong pro-oxidant whereas bilirubin is a strong antioxidant (2). Research studies suggest disregulation of heme oxygenases may contribute to oxidative stress-related diseases (2). There are three isozymes of heme oxygenases: HMOX1\/HO-1, HMOX2\/HO-2, and HMOX3\/HO-3 (1,2). HMOX1\/HO-1 is inducible by heme and other stress stimuli (1,3). HMOX2\/HO-2 and HMOX3\/HO-3 are constitutively expressed (1,3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nheme oxygenase (decycling) 2; Heme oxygenase 2; HMOX2; HO-2; HO2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Hm Mk\nSENSITIVITY: Endogenous\nMW (kDa): 36\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46800977854633,"sku":"32790S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-32790s","provider":"Iright","version":"1.0","type":"link"}