{"product_id":"cst-3329s","title":"CST,  3329S, MNDA (3C1) Rat Monoclonal Antibody","description":"Monoclonal Antibody for studying MNDA. Validated for WB,IHC,IF,F. Available in 2 sizes. Highly specific and rigorously validated in-house, MNDA (3C1) Rat Monoclonal Antibody (CST #3329) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunohistochemistry (Paraffin): 1:200 - 1:400\nImmunofluorescence (Immunocytochemistry): 1:200 - 1:400\nFlow Cytometry (Fixed\/Permeabilized): 1:400 - 1:800\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunohistochemistry (Paraffin), Immunofluorescence (Immunocytochemistry), Flow Cytometry (Fixed\/Permeabilized)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nMNDA (3C1) Rat Monoclonal Antibody detects endogenous levels of total MNDA protein.\nSpecies Reactivity: Human\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with nuclear extract from human granulocytes.\n\u003cb\u003eBackground\u003c\/b\u003e\nMNDA (myeloid cell nuclear differentiation antigen) is a transcription factor constitutively expressed in peripheral blood granulocytes and monocytes; low expression is also found in a subset of B cells (1,2). MNDA is a member of the interferon (IFN)-regulated 200 family of genes, which contain one or more copies of a partially conserved domain of 200 amino acid residues thought to mediate protein-protein interaction (3). MNDA may play a role in apoptosis and its expression is reduced in myelodysplastic syndromes (MDS) (4). MNDA has been proposed to be a marker for nodal marginal zone lymphoma (5).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nepididymis secretory sperm binding protein; MNDA; Myeloid cell nuclear differentiation antigen; PYHIN3\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H\nSENSITIVITY: Endogenous\nMW (kDa): 50\nSource\/Isotype: Rat IgG1","brand":"CST","offers":[{"title":"Default Title","offer_id":46800982409385,"sku":"3329S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-3329s","provider":"Iright","version":"1.0","type":"link"}