{"product_id":"cst-3389s","title":"CST,  3389S, LPP (8B3A11) Mouse Monoclonal Antibody","description":"Monoclonal Antibody for studying LPP. Validated for WB,IP,IHC,IF. Available in 2 sizes. Highly specific and rigorously validated in-house, LPP (8B3A11) Mouse Monoclonal Antibody (CST #3389) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\nImmunohistochemistry (Paraffin): 1:100\nImmunofluorescence (Immunocytochemistry): 1:100\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence (Immunocytochemistry)\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nLPP (8B3A11) Mouse Monoclonal Antibody detects endogenous levels of total LPP protein.\nSpecies Reactivity: Human, Mouse, Hamster, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a HIS-tagged recombinant fragment of human LPP.\n\u003cb\u003eBackground\u003c\/b\u003e\nLIM-containing lipoma-preferred partner (LPP) belongs to the zyxin family, members of which include LIMD1, ajuba, trip6 and zyxin. Three LIM domains at the carboxy-terminus characterize this family of proteins. Zyxin family members associate with the actin cytoskeleton and are components of both the cell-cell junction adhesive complex and the integrin-mediated adhesive complex (1). They shuttle in and out of the nucleus where they may function in transcriptional activation (1). LPP binding partners at cell-cell contacts include the actin regulator α-actinin (2) and the human tumor suppressor scrib which regulates cell migration and polarity (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nDKFZp779O0231; FLJ30652; FLJ41512; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma preferred partner; Lipoma-preferred partner; LPP\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M Hm Mk\nSENSITIVITY: Endogenous\nMW (kDa): 75\nSource\/Isotype: Mouse IgG1","brand":"CST","offers":[{"title":"Default Title","offer_id":46800988537001,"sku":"3389S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-3389s","provider":"Iright","version":"1.0","type":"link"}