{"product_id":"cst-3497s","title":"CST,  3497S, PHF2 (D45A2) Rabbit Monoclonal Antibody","description":"Monoclonal Antibody for studying PHF2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, PHF2 (D45A2) Rabbit Monoclonal Antibody (CST #3497) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nPHF2 (D45A2) Rabbit Monoclonal Antibody detects endogenous levels of total PHF2 protein.\nSpecies Reactivity: Human, Mouse, Rat, Monkey\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nMonoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp585 human PHF2 protein.\n\u003cb\u003eBackground\u003c\/b\u003e\nPlant homeodomain (PHD) finger protein 2 (PHF2) is a putative transcription factor. PHF2 contains a zinc finger-like PHD domain that is distinct from other classes of zinc finger motifs and is often found in proteins that influence chromatin structure (1). It also contains a Jumonji C (JmjC) domain, which may play a role in histone demethylation (2). The PHF2 gene is ubiquitously expressed in adult mouse tissues; however, the majority of PHF2 expression in the mouse embryo occurs in the neural tube and root ganglia (1). PHF2 mutations have been associated with both early- and late-onset breast carcinoma (3).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCENP-35; centromere protein 35; GRC5; JHDM1E; jumonji C domain-containing histone demethylase 1E; KDM7C; KIAA0662; Lysine-specific demethylase PHF2; MGC176680; PHD finger protein 2; PHF2\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R Mk\nSENSITIVITY: Endogenous\nMW (kDa): 150\nSource\/Isotype: Rabbit IgG","brand":"CST","offers":[{"title":"Default Title","offer_id":46799424159913,"sku":"3497S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-3497s","provider":"Iright","version":"1.0","type":"link"}