{"product_id":"cst-35136s","title":"CST,  35136S, STEEP Antibody","description":"Polyclonal Antibody for studying STEEP. Validated for Western Blotting,Immunoprecipitation. Highly specific and rigorously validated in-house, STEEP Antibody (CST #35136) is ready to ship.\n\n\u003cb\u003eProduct Usage Information\u003c\/b\u003e\nWestern Blotting: 1:1000\nImmunoprecipitation: 1:50\n\u003cb\u003eStorage\u003c\/b\u003e\nSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg\/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody .\n\u003cb\u003eProtocol\u003c\/b\u003e\nAvailable protocols: Western Blotting, Immunoprecipitation\n\u003cb\u003eSpecificity \/ Sensitivity\u003c\/b\u003e\nSTEEP Antibody recognizes endogenous levels of total STEEP protein.\nSpecies Reactivity: Human, Mouse, Rat\n\u003cb\u003eSource \/ Purification\u003c\/b\u003e\nPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human STEEP protein. Antibodies are purified by peptide affinity chromatography.\n\u003cb\u003eBackground\u003c\/b\u003e\nSTING ER exit protein (STEEP) is a highly conserved, ubiquitously expressed protein, which has been shown to be a positive regulator of the cGAS-STING signaling pathway. Mechanistically, research studies have demonstrated that STEEP constitutively interacts with STING to coordinate STING ER-to-Golgi trafficking, which is an essential step to ensure productive STING-dependent signaling and gene expression in response to viral infection (1).\n\u003cb\u003eAlternate Names\u003c\/b\u003e\nCXorf56; FLJ22965; MRX107; STEEP1; STING ER exit protein; STING1 ER exit protein 1; UPF0428 protein CXorf56\n\n\u003cb\u003eSpecification\u003c\/b\u003e\n\nREACTIVITY: H M R\nSENSITIVITY: Endogenous\nMW (kDa): 28\nSOURCE: Rabbit","brand":"CST","offers":[{"title":"Default Title","offer_id":46799425700009,"sku":"35136S","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/products\/cst-35136s","provider":"Iright","version":"1.0","type":"link"}